ADME-Enabling Technologies in Drug Design and Development by Donglu Zhang,Sekhar Surapaneni PDF

By Donglu Zhang,Sekhar Surapaneni

A accomplished consultant to state of the art instruments in ADME research

The final decade has visible super growth within the improvement of analytical innovations reminiscent of mass spectrometry and molecular biology instruments, leading to very important advances in drug discovery, quite within the quarter of absorption, distribution, metabolism, and excretion (ADME).

ADME-Enabling applied sciences in Drug layout and improvement specializes in the present cutting-edge within the box, offering a entire evaluation of the newest instruments for producing ADME facts in drug discovery. It examines the broadest attainable diversity of accessible applied sciences, giving readers the knowledge they should decide on the fitting software for a given program, a key considered necessary for acquiring favorable leads to a well timed style for regulatory filings. With over thirty contributed chapters by means of a world workforce of specialists, the ebook provides:

  • A thorough exam of present instruments, masking either electronic/mechanical applied sciences and biologically dependent ones

  • Coverage of purposes for every know-how, together with key parameters, optimum stipulations for meant effects, protocols, and case studies

  • Detailed dialogue of rising instruments and strategies, from stem cells and genetically transformed animal versions to imaging technologies

  • Numerous figures and diagrams through the text

Scientists and researchers in drug metabolism, pharmacology, medicinal chemistry, pharmaceutics, toxicology, and bioanalytical technological know-how will locate ADME-Enabling applied sciences in Drug layout and improvement a useful consultant to the total drug improvement procedure, from discovery to regulatory issues.

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ADME-Enabling Technologies in Drug Design and Development by Donglu Zhang,Sekhar Surapaneni

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